This is the definitive handbook for space crews living and working in zero gravity, as well as for the wide community of scientists, physicians and engineers who support them. It offers advice on physiological and medical problems of bone loss, kidney stones, motion sickness, muscle loss, loss of balance, orthostatic intolerance, weight loss, radiation exposure, as well as on gender differences and extra-vehicular activity. Additional topics include preparatino for flight, long-duration medical planning and rehabilitation. This is the first book to combine modern space physiology with practical advice.